A. Introduction.- I. Alfred Kohn and the Concept of Paraganglionic Cells and Tissues.- II. Max Watzkas Review on Paraganglia.- III. Notes on Terminology.- IV. Paraganglia and the APUD Cell Concept.- V. Paraganglia and the Concept of Paraneurons.- B. Morphological and Histochemical Methods for the Study of Paraganglionic Cells.- I. Fine Structural Morphology and Electron Microscopic Cytochemistry of Catecholamines.- 1. Primary Fixation with Metal Salts.- 2. Primary Fixation with Aldehydes.- a) Glutaraldehyde/Dichromate.- b) Glutaraldehyde/Osmium Tetroxide.- 3. Uranaffin Reaction.- 4. Staining of Ultrathin Sections.- a) Lead Citrate.- b) Argentaffin Reaction.- II. Light Microscopic Methods for the Study of Paraganglionic Cells.- 1. Chromaffin Reaction.- 2. Argentaffin Reaction.- 3. Iodate Oxidation.- 4. Schmorls Ferric Ferricyanide Reaction.- 5. Other Staining Methods.- 6. Fluorescence Methods.- a) Fixation in Aqueous Solutions.- b) Freeze-Dried Tissue.- c) Combination with Other Methods.- III. Immunocytochemistry of Enzymes Involved in Catecholamine Synthesis.- IV. Staining Methods for Proteins.- 1. Lead Haematoxylin.- 2. Masked Metachromasia.- 3. Coriphosphine O.- V. Quinacrine Fluorescence.- C. General Morphology of Paraganglionic Cells and Tissues.- I. The Chromaffin (Paraganglionic) Cell.- 1. Terminology.- 2. Cytology.- a) Nucleus.- b) Perikaryon and Cell Organelles.- c) Cilia.- d) Morphology of the Specific Granules.- ?) Large Granules.- ?) Small (Cored) Vesicles.- e) Origin and Fate of Specific Granules.- f) Shape of Paraganglionic Cells.- g) Synaptic Connections of Paraganglionic Cells.- ?) Efferent Synapses.- ?) Afferent Synapses.- ?) Reciprocal Synapses.- ?) Inhibitory Synapses?.- ?) Special Axon Terminals.- h) Contact Regions Between Paraganglionic Cells.- i) Mitoses.- 3. Catecholamines in Paraganglionic Cells.- a) Chromaffin Reaction.- b) Argentaffin Reaction.- c) Fluorescence Histochemistry.- d) Enzymes Synthesizing Catecholamines.- e) Chemical DeterminlÓ>