Pharmacokinetics A Modern View [Paperback]

Sidney Riegelman, the Man, His Work and His Impact.- 1. Sidney Riegelman  The Wisconsin Years.- 2. Sidney Riegelman  Friend and Colleague.- 3. Signey Riegelman  The Educator.- 4. Sidney Riegelman  The Scientist.- 5. Sidney Riegelman  His Contributions to Public Policy in Pharmacy and the Pharmaceutical Sciences.- 6. Sidney Riegelman  Contributions at the Clinical Interface.- Biopharmaceutics  Drug Delivery.- 7. Personal Experiences in the Early Days of Biopharmacy and Pharmacokinetics.- 8. Modern Pharmaceutical Dosage Forms.- 9. Specificity of Esterases and Effect of Structure of Prodrug Esters of Acylated Acetaminophen on Hydrolytic Reactivity.- 10. Transdermal Absorption: A Unique Opportunity for Drug Delivery.- 11. Pharmacokinetics and Pharmaceutical Technology.- 12. Bioavailability and Pharmacokinetics in Drug Development.- Pharmacokinetics  Concepts, Theory and Application.- 13. Clearance  Models, Validation and Implications.- 14. Estimation of an Effective Half-Life.- 15. Pharmacokinetic Aspects of Nonlinear Drug-Protein Binding.- 16. Unusual Pharmacokinetics.- Pharmacokinetics and Drug Metabolism.- 17. Assessment and Prediction of In Vivo Oxidative Drug Metabolizing Activity.- 18. Pharmacokinetic and Pharmacological Aspects of Polymorphic Drug Oxidation in Man.- 19. Problems in Correlating In Vitro and In Vivo Studies of Drug Metabolism.- 20. Integral Procedures in Pharmacokinetics and Their Application to the Parameter Determination of Appearing Metabolites.- 21. Pharmacokinetics at the Interface Between Pharmacology and Physiology.- Pharmacokinetics  Drug Dosing and Drug Effects.- 22. Methods for Drug Dosage Individualization: Past, Present and Future.- 23. Treatment of Depression  Pharmacokinetic and Pharmacogenetic Considerations.- 24. Kinetics of Drug Action.- Pharmacokinetics and Biopharmaceutics of Chemotherapeutic and Immunosuppressive Agents.- 25. Cancer Drug Delivery Systems: Macromolecular Prodrugs of Mitomycin C.- 26. Organ Variation inló!