All the important pharmacological interactions affecting thyroid function are described in this book. The first section is devoted to the physiology and biochemistry of thyroid disease, putting the pharmacological interactions into perspective. The second section reviews all the important pharmacological effects on thyroid function and also deals with the impact of other environmental agents. The chapters are written by internationally recognised experts and extensively referenced to provide an up-to-date review of the pharmacological interactions important to the thyroid and its diseases.With contributions by numerous experts.All the important pharmacological interactions affecting thyroid function are described in this book. The first section is devoted to the physiology and biochemistry of thyroid disease, putting the pharmacological interactions into perspective. The second section reviews all the important pharmacological effects on thyroid function and also deals with the impact of other environmental agents. The chapters are written by internationally recognised experts and extensively referenced to provide an up-to-date review of the pharmacological interactions important to the thyroid and its diseases.1 Introduction: Clinical Aspects of Thyroid Treatment.- A. Introduction.- B. Choices of Treatment for the Hyperthyroidism of Graves Disease.- I. Iodine-131 Therapy.- 1. Acceptability of Irradiation.- 2. Gastric Carcinoma.- 3. Ophthalmopathy.- 4. Calcitonin Deficiency.- II. Thyroid Surgery.- III. Antithyroid Drug Therapy.- C. Subclinical Hyperthyroidism.- D. Correct Dose of Thyroxine in Primary Hypothyroidism.- E. Subclinical Hypothyroidism: Treatment or Not?.- References.- 2 Control of TRH and TSH Secretion.- A. Introduction.- B. Negative Feedback Action of Thyroid Hormones.- C. Structure and Actions of TRH.- D. Structure and Actions of Somatostatin.- E. Actions of Neurotransmitters.- F. Actions of Cytokines and Inflammatory Mediators.- G. Physiological and lSÑ