Philosophy of Molecular Medicine Foundational Issues in Research and Practice [Hardcover]

Philosophy of Molecular Medicine: Foundational Issues in Theory and Practiceaims at a systematic investigation of a number of foundational issues in the field of molecular medicine. The volume is organized around four broad modules focusing, respectively, on the following key aspects: What are the nature, scope, and limits of molecular medicine? How does it provide explanations? How does it represent and model phenomena of interest? How does it infer new knowledge from data and experiments? The essays collected here, authored by prominent scientists and philosophers of science, focus on a handful of mainstream topics in the philosophical literature, such as causation, explanation, modeling, and scientific inference. These previously unpublished contributions shed new light on these traditional topics by integrating them with problems, methods, and results from three prominent areas of contemporary biomedical science: basic research, translationaland clinical research, and clinical practice.

Introduction

Chap. 1: Molecular medicine: the clinical method enters the lab. What tumor heterogeneity and primary tumor culture teach us

Chap. 2: Personalized Medicine: Historical Roots of a Medical Model

Chap. 3: From the concept of genetic disease to the geneticization of diseases: analyzing and solving the paradox of contemporary medical genetics

Marie Darrason

Chap. 4: Molecular complc¼