Photodynamic Therapy Basic Principles and Clinical Applications [Hardcover]

Covering all aspects of photodynamic therapy, 70 expert contributors from the fields of photochemistry, photobiology, photophysics, pharmacology, oncology and surgery, provide multidisciplinary discussions on photodynamic therapy - a rapidly-developing approach to the treatment of solid tumours.;Photodynamic Therapy: Basic Principles and Clinical Applications describes the molecular and cellular effects of photodynamic treatment; elucidates the complex events leading to photodynamics tissue destruction, particularly vascular and inflammatory responses; discusses the principles of light penetration through tissues and optical dosimetry; examines photosensitizer pharmacology and delivery systems; reviews in detail photosensitizer structure-activity relationships; illustrates novel devices that aid light dosimetry and fluorescence detection; and extensively delineates clinical applications, including early diagnosis and treatment.;A comprehensive and up-to-date reference, this book should be useful for oncologists, pharmacologists, surgeons, photobiologists, optical engineers, laser technicians, biologists, physicists, chemists and biochemists involved in cancer research, as well as graduate-level students in these disciplines.Historical perspective, Thomas J. Dougherty, et al. Part 1 Molecular and cellular effects of photodynamic therapy: fluorescence and photodynamic effects of phthalocyanines and porphyrins in cells, Johan Moan, et al; photodynamic therapy - membrane and enzyme photobiology, Tom M.A.R. Dubbleman, et al; cellular targets of photodynamic therapy as a guide to mechanisms, Russell Hilf; cellular stress responses following photodynamic therapy, Stefan W. Ryter, et al; basic photobiology and mechanisms of action of phthalocyanines, Ehud Ben-Hur; cationic sensitizers, combination therapies, and new methodologies, Allan R. Oseroff; bacterial and viral photodynamic inactivation, Zvi Malik, et al. Part 2 Tissue effects of photodynamic therapy: determinants foló>