Physical Activity, Dietary Calorie Restriction, and Cancer [Hardcover]

The World Health Organization estimates that 25 percent of common cancers can be prevented through regular physical activity and weight control. Common cancers linked to overweight/obesity and a sedentary lifestyle include breast, colon, endometrium, pancreas, renal, esophageal, and several others. There are several plausible mechanisms linking lack of physical activity and increased adiposity to cancer risk, supported by results from animal experiments and human intervention studies.

The WHO estimates that physical activity and weight control could prevent a quarter of common cancers. This book shows how obesity and sedentary lifestyles adversely affect cancer risk and survival for individuals, and analyzes the causal mechanisms.

The World Health Organization estimates that 25 percent of common cancers can be prevented through regular physical activity and weight control. Common cancers linked to overweight/obesity and a sedentary lifestyle include breast, colon, endometrium, pancreas, renal, esophageal, and several others. There are several plausible mechanisms linking lack of physical activity and increased adiposity to cancer risk, supported by results from animal experiments and human intervention studies.

Chapter 1: IntroductionAnne McTiernan, MD, PhDRachel Ballard-Barbash, MD, MPHLinda Nebeling, PH.D., MPH, RD, FADAChapter 2: Epidemiology of overweight/obesity and cancer riskDr Andrew Renehan PhD FRCSChapter 3: Epidemiology of physical activity and cancer risk.Becky SpeckKathryn Schmitz, PhDI-Min Lee, MD, ScDAnne McTiernan, MD, PhDChapter 4: Dietary energy restriction, exercise, and mammary carcinogenesisHenry Thompson, PhDChapter 5: Calorie restriction, exercise, and colon cancer prevention: a mechanistic perspectiveConnie Rogers, PhDSusan Perkins, PhDSteve Hursting, PhDChapter 6: Mechanisms linking obesity to cancer risk in humansIkuyo Imayama, MD, PhD, Caitlin Mason, PhD, Catherine Duggan, PhDChapter l3&