A Practical Guide to Human Cancer Genetics [Paperback]

This is a comprehensive 2006 guide to the diagnosis, clinical features and management of inherited disorders conferring cancer susceptibility.This is a comprehensive guide to the diagnosis, clinical features and management of inherited disorders conferring cancer susceptibility. This 2006 edition was fully up-dated with more molecular, screening and management information. It covers risk analysis, predictive testing and genetic counselling for individuals with a family history of cancer.This is a comprehensive guide to the diagnosis, clinical features and management of inherited disorders conferring cancer susceptibility. This 2006 edition was fully up-dated with more molecular, screening and management information. It covers risk analysis, predictive testing and genetic counselling for individuals with a family history of cancer.This is a comprehensive and up-to-date guide to the diagnosis, clinical features and management of inherited disorders conferring cancer susceptibility. This new edition is fully updated with much more molecular, screening and management information. It covers risk analysis and genetic counseling for individuals with a family history of cancer, and also discusses predictive testing and the organization of the cancer genetics service. It aims to provide such details in a practical format for geneticists and clinicians in all disciplines. This book differs from others in the field in that it is a practical handbook for easy reference for a wide clinical audience. There is a large reference list for further details, as well as information about the genes causing mendelian cancer predisposing condition and their mechanism of action.Part I: 1. Genetic counselling in a familial cancer clinic; Part II. Genetics of Human Cancers by Site of Origin: 2. Central nervous system; 3. Eye; 4. Cardiorespiratory system and thorax; 5. Endocrine system; 6. Gastrointestinal system; 7. Reproductive system; 8. Urinary system; 9. Blood and lymph; 10. MusculoskeletlĻ