Preventive and Predictive Genetics Towards Personalised Medicine [Hardcover]

Pharmacogenomics supports personalized medicine by translating genome-based knowledge into clinical practice, offering enhanced benefit for patients and health-care systems at large. Current routine practice for diagnosing and treating patients is conducted by correlating parameters such as age, gender and weight with risks and expected treatment outcomes.?In the new era of personalized medicine the healthcare provider is equipped with improved ability to prevent, diagnose, treat and predict outcomes on the basis of complex information sources, including genetic and genomic data.? Targeted therapy and reliable prediction of expected outcomes offer patients access to better healthcare management, by way of identifying the therapies effective for the relevant patient group, avoiding prescription of unnecessary treatment and reducing the likelihood of developing adverse drug reactions.

Introduction

Preventive and Predictive Genetics: A perspective
Godfrey Grech, Christian Scerri, Jeanesse Scerri, Tomris Cesuroglu

Roadmap to Drug Development Enabled by Pharmacogenetics
James P Bishop, Sonal B Halburnt, Patrick A Akkari, Scott Sundseth, Iris Grossman

Preventative and Predictive Genetics: Towards Personalised Medicine
Aiden Flynn, Craig Ledgerwood & Caroline OHare

Pharmacokinetics and Pharmacogenetics: bringing the magic bullet closer to reality
Janet Mifsud, ?Marc Maliepaard

Pharmacogenetics of Adverse Drug Reactions
Richard Myles Turner, Munir Pirmohamed

Pharmacogenomics for haemoglobinopathies therapeutics
Aikaterini Gravia, Vasiliki Chondrou, Theodora Katsila, George P. Patrinos

Pharmacogenetics of Neurodegenerative Disorders
Ram?n Cacabelos, Clara Torrellas, Pablo Cacabelos, Mar?a J. Villanueva, Sergio Pi?eiro, Cristina Solveira

PharmacoglÖ