Volume II features a variety of animal and human prion diseases, including the newly-identified atypical forms of bovine spongiform encephalopathy and scrapie in animals, and variably protease-sensitive prionopathy in humans, prions in the environment, Tau pathology in human prion disease, transmission of the disease by blood transfusion, mammalian and non-mammalian models, conventional and advanced diagnoses, prion-specific antibodies, as well as decontamination of prions and development of therapeutics of prion diseases, such as the application of immunomodulation. This volume provides up-to-date knowledge about the etiology, pathogenesis, classification, histopathological, and clinical aspects of the highly publicized animal and human prion diseases.
Volume II covers the etiology, pathogenesis, classification, histopathological and clinical aspects of animal and human prion diseases, including decontamination of prions and development of therapeutics for prion diseases, such as immunomodulation.
Chapter 1??? Bovine Spongiform Encephalopathy
Gianluigi Zanusso, Salvatore Monaco
Chapter 2??? Classical and Atypical Scrapie in Sheep and Goats
Christine Fast, Martin H. Groschup
Chapter 3 Chronic wasting disease and the development of research models
Glenn Telling
Chapter 4??? Sporadic Human Prion Disease
Pierluigi Gambetti
Chapter 5??? Environmentally-acquired Transmissible Spongiform Encephalopathy
Paul Brown
Chapter 6??? Prions in the Environment
Shannon L. Bartelt-Hunt, Jason C. Bartz, Samuel E. Saunders
Chapter 7??? The Spectrum of Tau Pathology in Human Prion Disease
Gabor G. Kovacs, Herbert Budka
Chapter 8??? Risk of Transmission of Creutzfeldt-Jakob Disease by Blood Transfusion
Alexander H. Peden, Mark W. Head, James W. Irolc(