Process Chemistry in the Pharmaceutical Industry [Hardcover]

Providing guidance for chemists and other scientists entering pharmaceutical discovery and development, this up-to-the-minute reference presents contributions from an international group of nearly 50 renowned researchersoffering a solid grounding in synthetic andphysical organic chemistry, and clarifying the roles of various specialties in the development of new drugs.

Featuring over 1000 references, tables, and illustrations, Process Chemistry in the Pharmaceutical Industryis sure to find its way to the bookshelves of organic, physical, analytical, process, and medicinal chemists and biochemists; pharmacists; and upper-level undergraduate and graduate students in these disciplines.Overview

Process Chemistry in the Pharmaceutical Industry: An Overview, Kumar G. Gadamasetti

Strategy

Process Research and Development Strategy for Accelerated Projects, Christopher M. Cimarusti

Case Studies

A Practical Synthesis of Ifetroban Sodium, Richard H. Mueller
Synthesis of 5-Lipoxygenase Inhibitors, Ivan Lantos and Richard Matsuoka
Chemistry of Vitamin D: A Challenging Field for Process Research, Masami Okabe
A Highly Optimized and Concise Large Scale Synthesis of a Purine Bronchodilator, Hans-J?rgen Federsel and Edib Jakupovic
Ontazolast: The Evolution of a Process, Vittorio Farina, Karl Grozinger, Hermann M?ller-B?tticher and Gregory P. Roth
Dilevalol Hydrochloride: Development of a Commercial Process, Derek Walker
Design and Development of Practical Syntheses of LY228729, a Potent 5HT_1aReceptor Agonist, Michael J. Martinelli and David L. Vals,