Progress in Medicinal Chemistry [Hardcover]

Progress in Medicinal Chemistry provides a review of eclectic developments in medicinal chemistry. This volume continues in the serial's tradition of providing an insight into the skills required of the modern medicinal chemist; in particular, the use of an appropriate selection of the wide range of tools now available to solve key scientific problems.

• Presents the latest research in the field of drug discovery
• Publishes on a twice yearly basis to bring you the most innovative updates in medicinal chemistry
• Available as an online resource via ScienceDirect

1. The Journey to the Discovery of Boceprevir: an NS3-NS4 HCV Protease Inhibitor for the Treatment of Chronic Hepatitis C - Kevin Chen & George Njoroge
2. A Decade of Progress in the Discovery and Development of 'Atypical' Antipsychotics - Gregor Madconald & Jose Manuel Bartolome
3. Structural Trends amongst Second Generation Voltage-Gated Sodium Channel Blockers - Mark Kemp
4. Computational Analysis of Structure-Activity Relationships - Peter Gedeck, Peter Ertl & Christian Kramer

The latest in the series with a focus on biochemical targets and pharmacokinetics

Dr Geoff Lawton has extensive experience in new medicine discovery across many therapeutic areas in both large and small companies and is a co-inventor of a marketed drug (Cilazapril). He is a former Director of Chemistry at Roche UK, and Vice-president Chemistry and Preclinical Sciences within Roche Bioscience, Palo Alto, USA. He was for five years the research member of a global therapy area strategy planning team for inflammatory diseases, aligning research with the clinical development and marketing parts of the business.

From 2003 to 2007 he was founding Researclc(