Progress in Regional Cancer Therapy [Paperback]

Present knowledge in regional cancer therapy is presented in this volume. The latest research addresses the questions of optimal drug development, the best galenic form and schedule to control tissue distribution at the tumor site and efficient treatment of specific anatomical regions.Present knowledge in regional cancer therapy is presented in this volume. The latest research addresses the questions of optimal drug development, the best galenic form and schedule to control tissue distribution at the tumor site and efficient treatment of specific anatomical regions.Advances in Drug Delivery.- Advances in Drug Delivery to Cancer Patients: Introduction.- Technical Developments in the Delivery of Antineoplastic Agents.- Is There a Pharmacologic Rationale for Continuous Cancer Chemotherapy?.- Central Venous Access in Children Through a Fully Implantable Drug Delivery System.- Intraportal Chemotherapy for Colorectal Hepatic Metastases.- Liver Metastases.- Prophylactic and Adjuvant Regional Chemotherapy of the Liver in Colorectal Malignancies.- Randomized Multicenter Trial on Adjuvant Intraportal Chemotherapy for Colorectal Cancer (SAKK 40/81).- Enhancement of Cytotoxic Efficacy of 5-Deoxy-5-fluorouridine in Acetoxymethyl-methylnitrosamine-Induced Colorectal Adenocarcinomas in SD Rats by Locoregional Administration into the Inferior Mesenteric Artery.- Second Hepatic Resections in Patients with Liver Metastases from Colorectal Carcinoma.- Six Years of Experience with Local Chemotherapy of the Liver.- Regional Therapy of Hepatic Metastases: Prognostic Factors.- Regional Therapy with 5-Fluorouracil: Dependence of Systemic Concentrations on the Infusion Rate.- Combined Regional and Systemic Chemotherapy in Hepatic Metastases of Colorectal Carcinoma: Continuous IA Vs Simultaneous IA/IV FUDR Infusion.- Intra-arterial Chemotherapy of Liver Metastases.- Current Standards and Limits in Treatment of Hepatic Metastases.- Degradable Starch Microspheres in Intra-arterial Tumor Treatmls�