Prostate Cancer Methods and Protocols [Hardcover]

This volume presents methods and protocols on modern analysis of steroid receptor and prostate cancer function. Chapters detail androgen, androgen receptor action, anti-androgen enzalutamide, in vitro and in vivo models, imaging, gene fusions, and help facilitate studies with novel drugs including anti-androgens and chemotherapeutics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and cutting-edge, Prostate Cancer: Methods and Protocols aims to provide easily reproducible techniques.

1. Generation of Prostate Cancer Patient-derived Xenografts to Investigate Mechanisms of Novel Treatments and Treatment Resistance

Hung-Ming Lam, Holly M Nguyen, and Eva Corey

 

2. Methods to Study Angiogenesis in a Mouse Model of Prostate Cancer

Ana-Rita Pedrosa, Alexandre Trindade, and Ant?nio Duarte

 

3. Methodologies Applied to Establish Cell Cultures in Prostate Cancer

Anne T Collins

 

4. Protocols for Migration and Invasion Studies in Prostate Cancer

Arjanneke F. van de Merbel, Geertje van der Horst, Jeroen T. Buijs, and Gabri van der Pluijm

Geertje van der Horst, Maaike van der Mark, Henry Cheung, and Gabri van der Pluijm

 

6. Protocols for Tissue Microarrays in Prostate Cancer Studies

Tatjana Vl“Y