Proteomics in Functional Genomics Protein Structure Analysis [Hardcover]

A wealth of information has accumulated over the last few years on thehuman genome. The new insights have completely changed the focus ofprotein analysis. It is no longer time-consuming analysis of unknownproducts, but rather selective identifications of individual forms,modifications and processings, and overall analysis of global proteinoutputs from cells and tissues in health and disease.This book gears to the rising need of sensitive, accurate, and fastseparation and identification techniques in proteomics. It discussescurrent methodologies of modern protein analysis, from isolation andsample preparation, over analysis and identification, to finalcharacterization. Several evaluations concentrate on the now productiveapproaches of two-dimensional gel electrophoresis and mass spectrometry,but alternative methods and further perspectives are also outlined. Thebook includes an overlook over current databases to connect proteinanalysis data with all available information,...A wealth of information has accumulated over the last few years on thehuman genome. The new insights have completely changed the focus ofprotein analysis. It is no longer time-consuming analysis of unknownproducts, but rather selective identifications of individual forms,modifications and processings, and overall analysis of global proteinoutputs from cells and tissues in health and disease.This book gears to the rising need of sensitive, accurate, and fastseparation and identification techniques in proteomics. It discussescurrent methodologies of modern protein analysis, from isolation andsample preparation, over analysis and identification, to finalcharacterization. Several evaluations concentrate on the now productiveapproaches of two-dimensional gel electrophoresis and mass spectrometry,but alternative methods and further perspectives are also outlined. Thebook includes an overlook over current databases to connect proteinanalysis data with all available information,...Proteome mapping by two-lı