Purines and Myocardial Protection [Paperback]

A critical review of the most up-to-date research on purines and myocardial protection. The role of purines in reversible `myocardial stunning' and irreversible (myocardial infarction) ischemic injury, ventricular arrhythmias, and ischemic preconditioning is discussed in detail, by experts. All reviews address recent and rather controversial issues on purines and myocardial protection. Mechanisms of cardioprotection of exogenous versus endogenous purines are discussed in detail. The contribution of internationally recognized experts in the field of purines and cardiovascular physiology and in myocardial protection makes this a unique and interesting book for clinicians, basic scientists and students.A critical review of the most up-to-date research on purines and myocardial protection. The role of purines in reversible `myocardial stunning' and irreversible (myocardial infarction) ischemic injury, ventricular arrhythmias, and ischemic preconditioning is discussed in detail, by experts. All reviews address recent and rather controversial issues on purines and myocardial protection. Mechanisms of cardioprotection of exogenous versus endogenous purines are discussed in detail. The contribution of internationally recognized experts in the field of purines and cardiovascular physiology and in myocardial protection makes this a unique and interesting book for clinicians, basic scientists and students.Part I: Purine Metabolism in the Heart 1. Physiologic and Pathophysiologic Significance of Purine Metabolism in the Heart; A.-S.A. Abd-Elfattah, et al. 2. Purine Metabolism in the Ischemic Canine and Human Immature Myocardium Deficient of 5?-Nucleotidase; A.- S.A. Abd-Elfattah, et al. 3. Cardiac Adenosine Metabolism: Physiological Implications; A. Deusson. 4. Purines Metabolism in Human Cardiomyocytes and Endothelium-Implications for Protection of the Heart during Cardiac Surgery; R.T. Smolenski, M. Yacoub. 5. Assessment of Interstitial Fluid Adenlƒ~