Pyrazolones, Pyrazolidones, and Derivatives [Hardcover]

The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects – properties, synthesis, reactions, physiological and industrial significance – of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.

Part 1. Chemistry

Chapter I. General

1. Introduction 3

2. Historical 4

3. Structure 5

4. Synthesis 9

5. Physical Properties 10

6. Chemical Properties 11

Chapter II. Pyrazolin-5-ones

1. Introduction 13

2. Unsubstituted Alkyl, Alicyclic, Aralkyl, Aryl and Heterocyclic Substituted Derivatives 13

A. 2-Pyrazolin-5-ones 13

(1) Syntheses 13

(2) Physical Properties 18

(3) Chemical Properties 19

(4) Hydroxyalkyl Types 29

(5) Aminoalkyl Types 30

(6) Bis(2-pyrazolin-5-ones) 31

B. 2-Pyrazolin-5-thiones 40

C. 5-Imino-2-pyrazolines 41

D. 3-Pyrazolin-5-ones 46

(1) Syntheses 46

(2) Properties 49

(3) Bis(3-pyrazoIin-5-ones) 56

E. 3-Pyrazolin-5-thiones and -5-slã7