Regulated Proteolysis in Microorganisms [Paperback]

This book contains an extensive collection of critical reviews, from leading researchers in the field of regulated protein degradation. It covers the role of regulated proteolysis in a range of microorganisms (from Gram positive, Gram negative and pathogenic bacteria to Archaea and the Bakers yeast Saccharomyces cerevisiae).

Preface: Regulated proteolysis, from basic mechanism to pathogenicity; David A. Dougan

Section A: AAA+ proteolytic machines

1. Machines of destruction - AAA+ proteases and the adaptors that control them; E. Gur, R. Ottofuelling & D.A. Dougan

2. The AAA+ protease Lon; E. Gur

3. FtsH protease-mediated regulation of various cellular functions; T. Okuno & T. Ogura

Section B: Regulatory proteolysis in bacteria

4. Regulated proteolysis in Bacillus subtilis; N. Moliere & K. Turgay

5. Regulation of stress response pathways in Escherichia coli by proteolysis; D. Micevski &, D.A. Dougan

6. Regulation of the SigmaE stress response; S.E. Barchinger & S.E. Ades

7. Pathogenic bacteria: protein degradation and virulence; D. Frees, L. Br?ndsted & H. Ingmer

Section C: Regulated proteolysis in yeast

8. Roles of Cdc48 in regulated protein degradation in yeast; A. Buchberger

9. The role of AAA+ proteases in mitochondrial protein biogenesis, homeostasis & activity control; K.N. Truscott, L. Ward & W. Voos

Section D: Ub-like protein modification and protein degral“T