Physicians, nurses, and safety experts comprehensively review sedation and analgesia to provide a completely new reference guide to safe sedation practices consistent with existing guidelines. Starting with an integrated review of the basic physiology and neurobiology of the sedated state, the authors proceed through clinical guidelines and practices, and conclude with an examination of quality-outcome measures and processes. They also review current mandates for safe sedation practices and address the key clinical issues of pharmacology, monitoring, and recovery. Special tables and figures throughout the book summarize protocols, regulatory requirements, recommended dosages, monitoring requirements, and quality assurance tools.Physicians, nurses, and safety experts comprehensively review sedation and analgesia to provide a completely new reference guide to safe sedation practices consistent with existing guidelines. Starting with an integrated review of the basic physiology and neurobiology of the sedated state, the authors proceed through clinical guidelines and practices, and conclude with an examination of quality-outcome measures and processes. They also review current mandates for safe sedation practices and address the key clinical issues of pharmacology, monitoring, and recovery. Special tables and figures throughout the book summarize protocols, regulatory requirements, recommended dosages, monitoring requirements, and quality assurance tools.Opioids, Sedation, and Sleep: Different States, Similar Traits, and the Search for Common MechanismsRalph Lydic, Helen A. Baghdoyan, and Jacinta McGinleyPractice Guidelines for Pediatric SedationDavid M. PolanerPractice Guidelines for Adult Sedation and AnalgesiaRandolph Steadman and Steve YunProcedure and Site-Specific Considerations for Pediatric SedationShobha MalviyaAdult Sedation by Site and ProcedureNorah N. NaughtonPharmacology of Sedative AgentsJoseph D. TobiasOpioids in the Management of Acute Pediatric PainlĂu