Selective Sweep [Paperback]

Selective Sweep deals with the theory and practice of detection of recent adaptive evolution at the genomic level from the patterns of DNA polymorphism. Recent advances in genomic sequencing provide the background for analysis of polymorphic sites in large chromosomal regions or even in whole genome, thus providing the tool for effective identification of loci that are under strong pressure of positive selection. For this reason, the studies of selective sweep, which formerly were of interest mostly to evolutionists, have become widely recognized and appreciated by the large biological community involved in identification of the targets of selection during speciation, host/pathogen interactions, and resistance to chemical agents.

Selective Sweep deals with the theory and practice of detection of recent adaptive evolution at the genomic level from the patterns of DNA polymorphism. Recent advances in genomic sequencing provide the background for analysis of polymorphic sites in large chromosomal regions or even in whole genome, thus providing the tool for effective identification of loci that are under strong pressure of positive selection. For this reason, the studies of selective sweep, which formerly were of interest mostly to evolutionists, have become widely recognized and appreciated by the large biological community involved in identification of the targets of selection during speciation, host/pathogen interactions, and resistance to chemical agents.

Preface.- Inferring Evolutionary History through Inter- and Intraspecific DNA Sequence Comparison: The Drosophila janus and ocnus Genes.- Rapid Evolution of Sex-Related Genes: Sexual Conflict or Sex-Specific Adaptations?- Selective Sweep in the Evolution of a New Sperm-Specific Gene in Drosophila.- Detecting Selective Sweeps with Haplotype Tests: Hitchhiking and Haplotype Tests.- A Novel Test Statistic fol3