In Silico Methods for Predicting Drug Toxicity [Paperback]

This detailed volume explores in silico methods forpharmaceutical toxicity by combiningthe theoretical advanced research with the practical application of the tools.Beginning with a section covering sophisticated models addressing the bindingto receptors, pharmacokinetics and adsorption, metabolism, distribution, andexcretion, the book continues with chapters delving into models for specifictoxicological and ecotoxicological endpoints, as well as broad views of themain initiatives and new perspectives which will very likely improve our way ofmodelling pharmaceuticals. Written for the highly successful Methods in Molecular Biology series,chapters include the kind of detailed implementation advice that is key forachieving successful research results.

Authoritative and practical, In Silico Methods for Predicting DrugToxicity offers the advantage of incorporating data and knowledge fromdifferent fields, such as chemistry, biology, -omics, and pharmacology, toachieve goals in this vital area of research.

1. QSARMethods

            Giuseppina Gini

 

Part I: Modeling aPharmaceutical in the Human Body

 

2. In Silico 3D-Modelling of Binding Activities

            Stefano Moro, MattiaSturlese, Antonella Ciancetta, and Matteo Floris

 

3. Modeling Pharmacokinetics

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