In Silico Systems Biology [Paperback]

Systems biology can now be considered an established and fundamental field in life sciences. It has moved from the identification of molecular 'parts lists' for living organisms towards synthesising information from different 'omics'-based approaches to generate and test new hypotheses about how biological systems work. In In Silico Systems Biology: Methods and Protocols, expert researchers in the field detail a practical set of chapters based often on actual materials used and develop for face-to-face training with examples and case studies.? Written in the highly successful Methods in Molecular Biology? series format, chapters include introductions to their respective topics, step-by-step workflows, and key tips on troubleshooting and avoiding known pitfalls.

?Authoritative and practical, In Silico Systems Biology: Methods and Protocols seeks to aid scientists in the further study of network biology and mathematical models of biological systems.

This Methods in Molecular Biology book offers detailed coverage of current techniques in network biology and mathematical models of biological systems. Includes step-by-step workflows, as well as key tips on troubleshooting and avoiding known pitfalls.

1. Defining Systems Biology: A Brief Overview of the Term and Field

Maria Victoria Schneider

?2. Approaches to Modelling Gene Regulatory Networks - A Gentle Introduction

Thomas Schlitt

3. Integration of Genomic Information with Biological Networks using Cytoscape

Anna Bauer-Menren

4. Visualization and Analysis of Biological Networks

Pablo Porras Mill?n

?5. Modeling Signaling Networks with Different Formalisms:? A Preview

Aidan MacNamara, David Henriques, and Julio Saez-Rodriguez

?6. From a Biological Hypothesis to the? Construction of a Mathemld