The Advanced Study Institute brought together researchers in the main areas of special functions and applications to present recent developments in the theory, review the accomplishments of past decades, and chart directions for future research. Some of the topics covered are orthogonal polynomials and special functions in one and several variables, asymptotic, continued fractions, applications to number theory, combinatorics and mathematical physics, integrable systems, harmonic analysis and quantum groups, Painlev? classification.Proceedings of the NATO Advanced Study Institute on Special Functions 2000, held in Tempe, Arizona, USAThe Advanced Study Institute brought together researchers in the main areas of special functions and applications to present recent developments in the theory, review the accomplishments of past decades, and chart directions for future research. Some of the topics covered are orthogonal polynomials and special functions in one and several variables, asymptotic, continued fractions, applications to number theory, combinatorics and mathematical physics, integrable systems, harmonic analysis and quantum groups, Painlev? classification.Preface. Foreword. Bailey's transform, lemma, chains and tree; G.E. Andrews. Riemann-Hilbert problems for multiple orthogonal polynomials; W. Van Assche, et al. Flowers which we cannot yet see growing in Ramanujan's garden of hypergeometric series, elliptic functions and q's; B.C. Berndt. Orthogonal rational functions and continued fractions; A. Bultheel, et al. Orthogonal polynomials and reflection groups; C.F. Dunkl. The bispectral problem: an overview; F.A. Gr?nbaum. The Bochner-Krall problem: some new perspectives; L. Haine. Lectures on q-orthogonal polynomials; M.E.H. Ismail. The Askey-Wilson function transform scheme; E. Koelink, J.V. Stokman. Arithmetic of the partition function; K. Ono. The associated classical orthogonal polynomials; M. Rahman. Special functions defined bl#O