This book discusses critical areas of progress in stem cell research, including the most recent research and applications of pluripotent embryonic cells, induced pluripotent cells, oligopotent tissue stem cells and cancer stem cells. The text covers basic knowledge of stem cell biology, stem cell ethics, development of techniques for applying stem cell therapy, the technology of obtaining appropriate cells for transplantation as well as the role of stem cells in cancer and how therapy may be directed to cancer stem cells. This new volume is essential reading for all scientists currently in the field or allied research areas, and those for those graduate students who envision a career in stem cells.?In its updated edition, this book reviews critical progress in stem cell biology, and discusses working with embryonic and fetal stem cells as well as induced pluripotent stem cells. Covers ethics, therapies,?obtaining?cells for transplantation and more.
Introduction to Stem Cells.- Contemporary Ethical Issues in Stem Cell Research.- Stem Cells from Early Mammalian Embryos.- Quantitative Approaches to Model Pluripotency and Differentiation in Stem Cells.- Growth Dynamics of Fetal Human Neural Stem Cells.- Immunobiology of Embryonic and Induced Pluripotent Stem Cell Transplantation.- Urodele Limb Regeneration: Mechanisms of Blastema Formation and Growth.- Mechanism of miR302-Mediated iPS Cell Generation.- Bioreactor Expansion of Pluripotent Stem Cells.- Generation of Hepatocyte-like Cells from Human Pluripotent Stem Cells.- Neural Differentiation from Pluripotent Stem Cells.- Generation of Anterior Foregut Derivatives from Pluripotent Stem Cells.- Commercial Opportunities for Induced Pluripotent Stem Cells.- Spermatogonial Stem Cells in Adult Mice and Men.- Characterization of the Hematopoietic Stem Cell Niche: Cellular and Molecular Analysis.- Glandular Stem Cells (GSCs): Stem Cells in Glandular Organs.- Human Mammary Epithelial Stem/Progenitor Cells.- Mammary Epil3+