The NATO-ASI conference Stem Cells and Their Potential for Clinical Application featured cutting-edge presentations ranging from laboratory research findings to the latest therapeutic applications. This book features contributions from many of the leading international scientists from North America and Western and Eastern Europe who participated in this conference. Articles cover a broad range of hot topics in stem cell and leukemia research.
Proceedings of the NATO Advanced Research Workshop on Stem Cells and Their Potential for Clinical Application, Kyiv and Foros,Ukraine, May 2006This publication was initiated on the occasion of the NATO-Advanced Study Institute (ASI) meeting Stem Cells and their potential for clinical application which took place from August 23 25, 2006 in Kyiv and from August 26 31, 2006 in Simeiz, Ukraine. The meeting was devoted to hot topics in Stem cell research such as Regulation of Haematopoietic and Non-haematopoietic Stem Cells, Clinical Application of Stem Cells, Preclinical Models and Gene Therapy. The editors are pleased that the original idea of a book could eventually be realised. This was made possible because of the willingness of many meeting participants to saddle themselves with the additional work of compiling their data and thoughts in form of an article for this edition. We are thus foremost grateful to all contributors for their valuable input. In accordance with the conferences main topics, the book is divided into five chapters - Haematopoietic stem cells and haematopoiesis, Biology of n- haematopoietic stem cells, Stem cells and malignancy, Cell processing; expansion and genetic modification and Clinical haematopoietic stem cell transplantation.I. HAEMATOPOIETIC STEM CELLS AND HAEMATOPOIESIS. Clonal Dominance After Reconstitution of the Haematopoietic System with Bone Marrow CellsRetrovirally Transduced with Murine CD34 Variants; G.von Keudell et al.- Function of the Membrane-Bound lCĪ