Susceptibility to Infectious Diseases The Importance of Host Genetics [Paperback]

A comprehensive review of research concerning genetic susceptibility to infectious diseases.In the last ten years, substantial progress has been made in identifying why some people are particularly susceptible to specific infectious diseases. Extensive evidence has now accumulated that host genes are important determinants of the outcome of infection for many common pathogens. This book, written by leading authorities, summarises the advances which have been made in understanding the complexity of host genetic susceptibility. The diseases covered include those of great public health inportance such as malaria and HIV, and those of current topical interest such as Creutzfeldt-Jakob disease.In the last ten years, substantial progress has been made in identifying why some people are particularly susceptible to specific infectious diseases. Extensive evidence has now accumulated that host genes are important determinants of the outcome of infection for many common pathogens. This book, written by leading authorities, summarises the advances which have been made in understanding the complexity of host genetic susceptibility. The diseases covered include those of great public health inportance such as malaria and HIV, and those of current topical interest such as Creutzfeldt-Jakob disease.Written by recognized authorities, this book summarizes significant advances in understanding the complexity of host genetic susceptibility. Substantial progress has been made over the last ten years in identifying why some people are particularly susceptible to specific infectious diseases. Extensive evidence has also been accumulated to reveal that host genes are important determinants of the outcome of infection for many common pathogens. Diseases covered include those of great public health inportance such as malaria and HIV, as well as those of current topical interest such as Creutzfeldt-Jakob disease.1. Introduction Richard Bellamy; 2. Application of genetic epidemiology to dissel³L