This volume focuses on methodological aspects of systems biology in order to provide a new theoretical approach with a robust and tailored experimental support. Chapters detail mathematical modeling, methodological issues, modulation of the collective behavior, metabolic, dynamic profiling, and quantitative morphological studies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Systems Biology aims to ensure successful results in the further study of this vital field.
1. Conceptual Challenges in the Theoretical Foundations of Systems Biology
Marta Bertolaso and Emanuele Ratti
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2. An Integrative Approach toward Biology, Organism
s, and Cancer
Carlos Sonnenschein and Ana M. Soto
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3. Conceptual Challenges of the Systemic Approach in Understanding Cell Differentiation
Andras Pald
i
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4. A Primer on Mathematical Modeling in the Study of Organisms and their Parts
Ma?l Mont?vil
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5. The Search for Systems Parameters
Alessandro Giuliani
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6
.? Inverse Problems in Systems Biology: A Critical Review
Rodolfo Guzzi, Teresa Colombo, and Paola Paci
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7. Systems Biology Approach and Mathematical Modeling for Analyzing Phase-space Switch during Epithe
lial-mesenchymal Transition
![Systems Biology [Hardcover]](/itemImage/2/6/8/4/2_931291.jpg "Systems Biology [Hardcover] xxx")