Tetraspanins [Paperback]

Tetraspanin proteins have recently emerged as a new class of modulators of various processes involving cell surface receptors, including cell migration and invasion, host immune responses, cell-cell fusion, and viral infection. The book summarises recent advances in the fields of biology in which the role of tetraspanins have been established and also covers the molecular evolution of the tetraspanin superfamily and structural aspects of the organisation of tetraspanin microdomains.This book surveys advances in biology in which the role of tetraspanins has been established, and also covers the molecular evolution of the tetraspanin superfamily and structural aspects of the organisation of tetraspanin microdomains.Foreword Chapter 1 Structural Bases for Tetraspanin Functions. Michel Seigneuret, H?l?ne Conjeaud, Hui-Tang Zhang and Xiang-Peng Kong Chapter 2 The Evolution of Tetraspanins Through a Phylogenetic Lens. Rob DeSalle, Tung-Tien Sun, Tjard Bergmann and Antonio Garcia-Espa?a Chapter 3 Organisation of the Tetraspanin Web. Eric Rubinstein, St?phanie Charrin and Michael G. Tomlinson Chapter 4 Dynamic Partitioning of Tetraspanins Within Plasma Membranes. Olga Barreiro, Francisco Sanchez-Madrid, C?dric Espenel and Pierre-Emmanuel Milhiet Chapter 5 Tetraspanins as Regulators of Protein Trafficking. Elena Odintsova and Fedor Berditchevski Chapter 6 The Role of Tetraspanins in Cell Migration and Intercellular Adhesion. Emilio Tejera, M?nica Sala-Vald?s, Vera Rocha-Perugini and Mar?a Y??ez M? Chapter 7 Genetic Evidence for Tetraspanin Functions. Martin E. Hemler Chapter 8 Tetraspanins in Lower Eukaryotes. Hiroki Moribe and Eisuke Mekada Chapter 9 The Role of Tetraspanin Complexes in Egg-Sperm Fusion. Virginie Barraud-Lange and Claude Boucheix Chapter 10 Tetraspanins and Immunity. Mark D. Wright and Shoshana Levy Chapter 11 Tetraspanins in Cancer. Leonie K. Ashman and Margot Z?ller Chapter 12 Uroplakins as Unique Tetraspanin Networks. Tung-Tien Sun, Gert Kreibich, Angel lÃ'