In Therapeutic Applications of Ribozymes and Riboswitches: Methods and Protocols, expert researchers in the field provide a complete overview of protocols used in the development of RNA molecule as drugs and drug target. These include methods and protocols on recent and precise RNA molecule approaches or studies in the development of an RNA therapeutic tool. We are convinced that these methods will help researchers from various domains of life sciences, including clinicians, biochemists and virologists. Written in the highly successful Methods in Molecular Biology?series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Therapeutic Applications of Ribozymes and Riboswitches: Methods and Protocols seeks to aid scientists in the further development of new therapeutic applications implicating RNA molecules or directly targeting harmful RNA.
This Methods in Molecular Biology book offers a complete overview of protocols used in the development of RNA molecule as drugs and drug target. Includes material and reagent lists, reproducible lab protocols, known pitfalls, troubleshooting tips and more.
1. Identification of Regulatory RNA in Bacterial Genomes by Genome-Scale Mapping of Transcription Start Sites
Navjot Singh and Joseph T. Wade
?2. Screening Inhibitory potential of anti-HIV RT RNA Aptamers
Margaret J. Lange and Donald H. Burke
?3. Design and Evaluation of Clinically Relevant SOFA-HDV Ribozymes Targeting HIV RNA
Robert J. Scarborough, Michel V. L?vesque, Jean-Pierre Perreault, and Anne Gatignol
?4. Directing RNase P-mediated Cleals,
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