Topics in Biostatistics [Paperback]

This book presents a multidisciplinary survey of biostatics methods, each illustrated with hands-on examples. It introduces advanced methods in statistics, including how to choose and work with statistical packages. Specific topics of interest include microarray analysis, missing data techniques, power and sample size, statistical methods in genetics. The book is an essential resource for researchers at every level of their career.

Basic Biostatistics presents a multidisciplinary survey of biostatics methods, each illustrated with hands-on examples. Methods range from the elementary, including descriptive statistics, study design, statistical interference, categorical variables, evaluation of diagnostic tests, comparison of means, linear regression, and logistic regression. These introductory methods create a portfolio of biostatistical techniques for both novice and expert researchers. More complicated statistical methods are introduced as well, including those requiring either collaboration with a biostatistician or the use of a statistical package. Specific topics of interest include microarray analysis, missing data techniques, power and sample size, statistical methods in genetics. Expert advice is given on when to seek statistical help, and how to conduct a meeting with the statistical collaborator or consultant. Basic Biostatistics is an essential resource for researchers at every level of their career.

Outline:1. Study Design-The BasicsHyun Ja Lim and Raymond Hoffmann, Medical College of Wisconsin1. Introduction2. Experimental Studies2.1 Randomized controlled studies2.2 Historically controlled studies2.3 Crossover studies2.4 Factorial designs2.5 Cluster or group allocation designs3. Randomization3.1 Complete or simple randomization3.2 Block randomization3.3 Stratified randomization4. Blinding/Masking5. Biases6. Analyses6.1 Compliance6.2 Intention-to-treat (ITT) analysis6.3 As received and per-protocol (PP) analysis6.4 Subgl“!