In recent years, intensive care and emergency medicine have emerged as new medical specialties. Better understanding of acute illness and continuous advances in technology have fostered rapid development of new forms of therapy. This volume provides updates in this rapidly expanding field and includes various topics presented by recognized experts in the field.In recent years, intensive care and emergency medicine have emerged as new medical specialties. Better understanding of acute illness and continuous advances in technology have fostered rapid development of new forms of therapy. This volume provides updates in this rapidly expanding field and includes various topics presented by recognized experts in the field.Circulatory Failure: The Importance of Tissue Oxygen Supply.- Cardiocirculatory Control Mechanisms in Health and Disease.- Can Primary Resuscitation Therapy Be Improved?.- Oxygen Transport and Utilization in Critically Ill Patients.- Oxygen Transport Following Major Trauma.- Limits of Hemodilution in Patients with Coronary Artery Disease.- Pathophysiology of Lactic Acidosis.- Transport and Consumption of Oxygen in Septic Shock.- New Aspects of Sepsis: Relevance to Shock and MOF.- The Molecular Basis of Shock: The Role of Cachectin.- Immunologic Abnormalities Following Hemorrhage and Trauma.- Update in Host Defence Mechanisms.- Selective Elimination of Oropharyngeal and Gastro-Intestinal Flora: A Step Forward in the Control of Infection in ICU?.- Effect of Selective Decontamination on Colonization and Infection Rate in Intensive Care Patients.- Pathogenesis of Gram-Negative Bacterial Infections.- Sepsis in Children: Different Pathophysiology, Different Treatment?.- Acute Respiratory Failure.- Adult Respiratory Distress Syndrome: Changing Concepts of Clinical Evolution and Recovery.- Role of Arachidonic Acid Metabolism in ARDS.- Leukocytes-mediated Pulmonary Injury.- PGE1 Administration in ARDS.- Inhalation Injury.- Respiratory Muscle Insufficiency in Neurl“\