Use of Nanoparticles in Neuroscience [Hardcover]

This volume discusses techniques to synthesize and functionalize nanoparticles, monitor their delivery and uptake, and identify and evaluate their lethal and non-lethal effects on the metabolic activity of the nervous system. The chapters in this book are divided into 4 sections: photo-stimulation, thermal stimulation, mechanical perturbation, and toxicity and physiological effects. The first 3 sections ?focus on nanoparticle interactions with external sources that disturb the neuronal system, while the 4th explores the effects of having nanoparticles in a neuronal system in the absence of external stimuli. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.

Cutting-edge and comprehensive, Use of Nanoparticles in Neuroscience is a valuable resource for graduate students and specialized researchers that want to learn techniques needed to quantify experiments that use nanoparticles in the nervous system.

Neuromethods Series Preface&

Preface&

Table of Contents&

Contributing Authors&

1. Optocapacitance Allows for Photostimulation of Neurons without Requiring Genetic Modification

Joao L. Carvalho-de-Souza, Jeremy S. Treger, David R. Pepperberg, and Francisco Bezanilla

2. Nanoparticle-Assisted Localized Optical Stimulation of Cultured Neurons

Flavie Lavoie-Cardinal, Charleen Salesse, Pierre-Luc Ayotte-Nadeau, and Paul De Koninck

3. Stimulation of Primary Auditory Neurons Mediated by Near-Infrared Excitation of Gold Nanorods